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Symbol
Name
ID
Cd74
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
MGI:96534
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
decreased B cell proliferation
abnormal T cell proliferation
decreased T cell proliferation
increased T cell proliferation
abnormal B cell differentiation
increased immature B cell number
arrested B cell differentiation
abnormal positive T cell selection
increased eosinophil cell number
increased neutrophil cell number
decreased B cell number
decreased CD4-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
decreased lymphocyte cell number
increased monocyte cell number
abnormal B cell physiology
decreased IgM level
abnormal T-helper 1 physiology
Availability Mouse Genotype
Cd74em1(IMPC)H/Cd74em1(IMPC)H
Cd74tm1Doi/Cd74tm1Doi
Cd74tm1Eae/Cd74tm1Eae
Cd74tm1Liz/Cd74tm1Liz *
Cd74tm1Liz/Cd74+ *
Cd74tm2Liz/Cd74tm1Liz
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm2(Cd74/MOG)Awai/Gt(ROSA)26Sor+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory